CicakmanHairi (Saiful Apek) is a loser who lives in Metrofulus. While working in the lab, he accidentally drinks coffee that has been contaminated by a virus-infected gecko. He soon finds himself doing the most insane things, such as sticking to walls, making chirping cicak noises and adding bugs to his menu. He turns to his best friend and apartment mate, Danny (Yusry Abdul Halim), and begs him to find the reason behind his strange antics. Meanwhile, the people of Metrofulus are constantly being infected by new strains of viruses, and the only cure seems to come only from Professor Klon's (Aznil Nawawi) lab. Suspecting something amiss, Hairi and Danny launch their own investigation and discover that Professor Klon is not only the creator of such viruses, but also has a more sinister plan up his sleeve, backed by his business partners, the Ginger Boys Ramlie and AC Mizal, who first tend to take revenge on Professor Klon's failed experiment on them; making their senses turn abnormal. This TimeAva Buhay, 21, who is ever loyal with her childhood best friend, Coby Martinez, 21, hopes that one day their special friendship will turn into a beautiful romance. However, the time they get to see each other is only during summer vacation. Until one summer, Coby needs to go to U.S to help his grandfather, Lolo Melchor, find his long lost love, Ofelia. Hence, this is the last time they’re going to see each other. This long distance “just friends” relationship lasts for years. Because of this, the chance to have a romantic relationship becomes elusive for both of them. After three years, fortunately, they get a chance to see each other again during Ava’s Japan trip. While Ava is up for an art workshop in Japan, Coby and Lolo Melchor are set to search for Ofelia. In this quest of love of Lolo Melchor, could this also be the right time for Coby and Ava to admit what they truly feel for each other?